The Mitochondrial Paradigm: Sourcing MOTS-c for Metabolic and Endurance ResearchIn the landscape of modern peptide science, research has moved beyond the cell nucleus. The most critical breakthroughs of 2026 are happening within the mitochondria. At the forefront of this shift is MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)—a uniqu